In its Global Hepatitis Report 2026, the United Nations health agency said hepatitis B and C, which account for 95% of hepatitis-related deaths worldwide, caused 1.34 million deaths in 2024, while more than 1.8 million new infections were recorded during the year.

WHO estimated that 287 million people were living with chronic hepatitis B or C infections in 2024, despite the availability of vaccines and highly effective treatments.“Progress is too slow and uneven,” WHO Director-General Tedros Adhanom Ghebreyesus said in a statement.“Many people remain undiagnosed and untreated due to stigma, weak health systems and inequitable access to care.

While we have the tools to eliminate hepatitis as a public health threat, urgent scale-up of prevention, diagnosis and treatment is needed,” he said.Hepatitis is an inflammation of the liver caused by infectious viruses and other agents, often leading to severe complications including liver failure, cirrhosis and cancer.

Of the five main viral strains, hepatitis B and C are the deadliest and remain among the world’s leading infectious disease killers.The WHO said fewer than 5% of the 240 million people living with chronic hepatitis B in 2024 were receiving treatment. For hepatitis C, only 20% of infected people have been treated since 2015.

In Africa, which carries the heaviest burden of hepatitis B infections, only 17% of newborns received the recommended birth-dose vaccine in 2024, raising concerns about continued mother-to-child transmission.

Six countries China, India, Indonesia, Nigeria, South Africa and Vietnam are among the top 10 globally for deaths linked to hepatitis B and C, the report said.“Every missed diagnosis and untreated infection due to chronic viral hepatitis represents a preventable death,” said Tereza Kasaeva, director of the WHO department overseeing hepatitis programs.

The agency said proven medical tools are already available. The hepatitis B vaccine protects more than 95% of recipients from both acute and chronic infection, while long-term antiviral treatment can help prevent severe liver disease in chronic cases.

For hepatitis C, short-course curative therapies lasting eight to 12 weeks can cure more than 95% of infections, WHO said.The agency pointed to United Kingdom, Egypt, Georgia and Rwanda as examples of countries demonstrating that hepatitis can be eliminated as a public health problem through sustained policy action and financing.

“Eliminating hepatitis is not a pipedream: it’s possible with sustained political commitment, backed by reliable domestic financing,” Tedros said.Since 2015, annual new hepatitis B infections have fallen by 32%, while hepatitis C-related deaths have declined by 12%, according to WHO data.

The initiative, known as the Big Catch-Up and led by the World Health Organization, UNICEF and Gavi, the Vaccine Alliance, concluded in March after a three-year effort to restore immunization coverage disrupted by the pandemic.

By the end of December 2025, the campaign had reached an estimated 18.3 million children aged under five across 36 countries in Africa and Asia, delivering more than 100 million vaccine doses, according to a joint statement. Of those, around 12.3 million children had never received any prior vaccination, while 15 million had not previously been immunized against measles.

Health systems worldwide faced severe disruption during the COVID-19 crisis, leading to missed routine immunizations and a resurgence of preventable diseases including measles and polio. The agencies said the campaign also strengthened national immunization systems by improving their ability to identify children who had previously been missed.

Tedros Adhanom Ghebreyesus said the initiative had helped reverse one of the pandemic’s major health setbacks by reaching children who had been excluded due to service disruptions.However, officials warned that significant obstacles persist.

The agencies highlighted declining foreign aid and widening gaps in routine immunization, noting that measles outbreaks have increased globally, with approximately 11 million cases reported in 2024.Kate O’Brien said growing politicization of vaccines and health issues posed a serious concern, even as trust in frontline health workers remained relatively strong.

Sania Nishtar pointed to the role of social media in amplifying misinformation, saying digital platforms often incentivize the spread of misleading or false content about vaccines.

Ephrem Lemango added that algorithm-driven amplification of anti-vaccine narratives, combined with reductions in global health funding, could undermine progress and risk reversing gains made through the campaign.